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雌激素和癌症
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雌激素和癌症
雌激素和癌症
新的研究显示,妇女的雌激素可以保护妇女,预防结肠直肠癌,意大利米兰药理学研究所的科学家发现如果妇女口服避孕药,发这种病的机会就会减少百分之二十。
领导这个研究的卡罗 拉威克说:“我们开始猜想是这个药里的雌激素保护了妇女,预防肠癌,现在我们的研究差不多证实了这一点。在将来,利用这个药里的抗癌物质,发展新的治疗方法是可能的。”
意大利癌症研究协会资助这个研究。这个发现刊登在英国的(癌症杂志)上,它与最近的一项研究很相似,这个研究说,激素替代疗法(HRT)能够保护妇女,预防结肠直肠癌。
美国癌症协会流行病学的领导米其尔 山说:“这些研究表明雌激素对结肠直肠癌有抑制作用。”
在过去的二十年里,因结肠直肠癌的死亡率,妇女比男子降低了更多。一些科学家相信这一部分要归功于妇女的口服避孕药和激素替代疗法里的雌激素。
世界卫生组织估计,去年全世界差不多有一百万人被诊断得了结肠直肠癌。美国癌症协会预计,今年将会有13,5000美国人会被诊断出得了结肠直肠癌。
米其尔·山说:“50岁以后多体检,有规率地锻炼身体和保持体重是减少结肠直肠癌发病机会的最好方法。” ----据 http://www.chron.com 休斯顿时报4月18日编译
Estrogen protection indicated Pill may suppress colorectal cancer Associated Press New research bolsters the theory that the female hormone estrogen might protect women from colorectal cancer.
Italian scientists have found that women had about a 20 percent lower chance of developing the disease if they used oral contraceptives.
"For a while now we have suspected that estrogen in the pill could protect against bowel cancer, and our research has gone some way to confirm this," said Dr. Carlo La Vecchia, who led the study. "In the future, it may be possible to develop new treatments that take advantage of the anticancer qualities of the pill."
The findings, published Monday in the British Journal of Cancer, are similar to those of a recent study which suggested that hormone replacement therapy, or HRT, could protect women from colorectal cancer to the same degree.
Over the past 20 years, death rates from bowel cancer have dropped more in women than in men. Some scientists believe this could be partly due to estrogen found in oral contraceptives and hormone replacement therapy.
That theory deserves more attention, according to Dr. Michael Thun, head of epidemiology at the American Cancer Society.
"How relevant these findings are to today's pill use is unclear because they relate mostly to older formulations," said Thun, who was not involved in the research. "But this does support the hypothesis that estrogen plays a role in suppressing colorectal cancer."
The study by researchers from the Institute of Pharmacological Research in Milan, Italy, pulled together the evidence from 19 international investigations into a possible link between birth control pills and cancer of the colon and bowel. It is the first comprehensive analysis of the topic.
Nearly 1 million people were diagnosed with colorectal cancer worldwide last year, the World Health Organization estimates. The American Cancer Society projects that more than 135,000 Americans will be diagnosed with the disease this year.
Regular screening after age 50, regular exercise and maintaining a healthy weight are considered the best ways to reduce the chances of developing colorectal cancer, Thun said.
The study was funded by the Italian Association for Cancer Research.

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