1、C.Bombardier,et al.,"Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis,"New Engl.J.Med.,New Engl.J.Med.,343(21):1520-8,23 November 2000.[14 institutions worldwide] *375PR

Citations  This Period (NovDec 01)         50

Rank  Last Period  (SepOct 01)              2

2、F.E.Silverstein,et al.,"Gastrointestinal toxicity with　celecoxib vs nonsteroidal anti-inflammatory drugs for　osteoarthritis and rheumatoid arthritis.The CLASS study: a　randomized controlled trial,"JAMA-J.Amer.Med.Assn.,284(10): 1247-55,13 September 2000.[12 U.S.institutions]  *350WL

Citations  This Period (Nov-Dec 01)         49

Rank  Last Period  (Sep-Oct 01)              5

3、S.Yusuf,et al.,"Effects of angiotensin-converting enzyme　inhibitor,ramipril,on cardiovascular events in high-risk　patients,"New Eng.J.Med.,342(3):145-53,20 January 2000.　[Hamilton Gen.Hosp.,Ont.,Canada]  *275ZT

Citations  This Period (Nov-Dec 01)         37

Rank  Last Period  (Sep-Oct 01)             1

4、P.M.Ridker,et al.,"C-reactive protein and other markers　of inflammation in the prediction of cardiovascular　disease in women,"New Engl.J.Med.,342(12):836-43,23 March　2000.[Brigham & Womens Hosp.,Boston,MA;Harvard U.Sch.Med.,　Boston;Childrens Hosp.,Boston]  *296FU

Citations  This Period (Nov-Dec 01)         32

Rank  Last Period  (Sep-Oct 01)             3

5、G.R.Bernard,et al.,"Efficacy and safety of recombinant　human activated protein C for severe sepsis,"New Engl.J.　Med.,344(10):699-709,8 March 2001.[9 institutions　worldwide]  *408AX

Citations  This Period (Nov-Dec 01)         30

Rank  Last Period  (Sep-Oct 01)             8

6、B.J.Druker,et al.,"Efficacy and  safety of a specific　inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid　leukemia,"New Engl.J.Med.,344(14):5 April 2001.[Oregon Hlth.Sci.U.,Portland;U.Texas,M.D.Anderson Canc.Ctr.,Houston;　Nova Pharmaceut.Corp.,E.Hanover,NJ;U.Calif.,Los Angeles]　*417XH

Citations  This Period (Nov-Dec 01)         29

Rank  Last Period  (Sep-Oct 01)              

7、A.Kugler,et al.,"Regression of human metastatic renal cell　carcinoma after vaccination with tumor cell-dendritic cell　hybrids,"Nature Medicine,6(3):332-6,March 2000.[U.Gottingen,　Germany；U.Tubingen,Germany;Humboldt U.,Berlin,Germany]*288TL

Citations  This Period (Nov-Dec 01)         31

Rank  Last Period  (Sep-Oct 01)             5

8、B.J.Druker,et al.,"Activity of a specific inhibitor of the　BCR-ABL tyrosine kinase in the blast crisis of chronic　myeloid leukemia and acute lymphoblastic leukemia with the　Philadelphia chromosome,"New Engl.J.Med.,344(14):1038-42,5 April 2001.[Oregon Hlth.Sci.U.,Portland;Univ.Calif.,Los　Angeles;U.Texas,M.D.Anderson Canc.Ctr.,Houston;Nova Pharmaceut.　Corp.,E.Hanover,NJ]  *417XH

Citations  This Period (Nov-Dec 01)         28

Rank  Last Period  (Sep-Oct 01)              

9、A.M.J.Shapiro,et al.,"Islet transplantation in seven　patients with type 1 diabetes mellitus using a　glucocorticoid-free immunosuppressive regimen,"New Engl.J.　Med.,343(4):230-8,27 July 2000.[U.Alberta,Edmonton,Canada]　337QC

Citations  This Period (Nov-Dec 01)         25

Rank  Last Period  (Sep-Oct 01)             6

10、G.G.Schwartz,et al.,"Effects of atorvastatin on early　recurrent ischemic events in acute coronary syndromes.The　MIRACL study:a randomized controlledtrial,"JAMA-J.Amer.Med.　Assn.,285(13):1711-8,4 April 2001.[13 institutions worldwide]　*415FR

Citations  This Period (Nov-Dec 01)         24

Rank  Last Period  (Sep-Oct 01)              

SOURCE:　ISIs Hot Papers Database